R&D Advisory Board

Professor Ashley I. Bush
MD, Ph.D
Research and Development Advisory Board

Professor Bush is the Australian Research Council Federation Fellow at the Mental Health Research Institute of Victoria (Australia) and a co-founding scientist of Prana.

Professor Bush studies the major proteins implicated in Alzheimer‘s disease that aggregate to cause plaques. Copper/zinc-binding proteins, whose physiochemical properties (e.g. solubility), are profoundly influenced by interaction with metal ions. Dr. Bush‘s lab has developed new drugs based on metals theory that are being tested in the clinic.

Professor Bush‘s lab also explores the causes of severe oxidative stress in the brain as it relates to Alzheimer‘s disease, as well as the relationship between amyloid deposition in the brain (the typical pathology of Alzheimer‘s disease) and oxidation injury.

Dr. Jeffrey L.Cummings (Chairman) - UCLA Alzheimer‘s Disease Center
Dr. Craig W.Ritchie - Imperial College London
Dr. Steven D. Targum - Oxford Bioscience Partners **
Professor Jean-Marc Orgogozo - University of Bordeaux
Professor Ashley Bush - Mental Health Research Institute
Professor Colin Masters - The University of Melbourne
Professor Rudolph Tanzi - Harvard Medical School, Massachusetts General Hospital

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